The Ketogenic Bible

Our good friend Dr. Dominic D’Agostino once said that ketogenic dieting “puts appetite back into our control.” There are several potential reasons for this. First, the ketogenic diet prevents drops in blood glucose, slightly elevates fatty acids, and robustly raises ketones, so our nutrient stat may recognize that we don’t need to eat (Paoli et al., 2015). This contrasts with low-fat diets, which promote between-meal drops in blood glucose, suppress fatty acids, and prevent the formation of ketones (Gibson et al., 2015). Second, ketosis prevents hunger hormones like ghrelin from rising, while some satiety hormones, like cholecystokinin (CCK), do not drop as they do with low-calorie diets (Sumithran et al., 2013). Finally, on a well-formulated ketogenic diet, the carbohydrates we do take in, ideally from high-fiber leafy green vegetables, can trigger greater mechanical signals of satiety due to their sheer volume (Ard et al., 2016). (Location 2293)